Robina Private Hospital Anti-Amyloid Therapy Referral

A referral for patients that have a formal diagnosis of Alzheimer’s disease and are seeking Lecanemab (Leqembi®) or Donanemab (Kisunla®) therapy.

Referrer Details


Patient Information


If yes, please provide name / relationship and phone number:

Patient Next of Kin

Patient GP Details

SECTION 1 — TRIAGE SUMMARY

Please consider the following before referral.

Requirement 

  • Confirmed Alzheimer's diagnosis

  • Amyloid confirmation (PET or CSF)

  • Brain MRI using GRE and SWI with ARIA, amyloid imaging abnormality assessment preferable and local access to MRI available such as patient can access the same machine for comparison.

  • APOE ε4 genotyping status

  • Baseline bloods, coagulation and renal function to consider.

  • Any Cardiac issues such as Atrial Fibrillation

  • MMSE

  • Care partner identified and engaged

SECTION 2 — AMYLOID STATUS (Confirmed positive)

Confirmation Method

TAU / SUPPLEMENTARY BIOMARKERS (If available)

SECTION 3 — NEUROIMAGING SUMMARY (MRI required within 6 months prior to initiation)

MRI Baseline ARIA eligibility checklist — all preferable to be absent or within acceptable limits:

  • MRI FindingMacrohemorrhage >1 cm

  • Microhemorrhages (number: ___)

  • Superficial siderosis

  • Cortical infarcts

  • Lacunar infarcts (number: ___)

  • Fazekas grade 3 White Matter Disease

  • Cerebral Amyloid Angiopathy

  • CAA features

  • Other major intracranial pathology

SECTION 4 — THERAPY REQUEST

SECTION 5 — SAFETY COSNIDERATIONS

  • No anticoagulant use (or risk formally assessed)

  • Blood pressure adequately controlled

  • No recent stroke / TIA (12 months)

  • No active malignancy

  • No active or unstable psychiatric disorder

  • No known serious hypersensitivity to monoclonal antibodies

  • Non-AD diagnoses excluded (FTD, LBD, vascular dementia)

  • Renal function acceptable (eGFR: ___)

  • Unstable arrythmia eg. AF, SVT

  • APOE STATUS 4/4

SECTION 6 — ADDITIONAL CLINICAL NOTES


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Submission of an online referral does not does not automatically constitute acceptance of the referral. We will contact your patient, and you will be advised of the outcome.

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